About Synedgen

Overview

Creating breakthrough therapeutics with glycomics

Synedgen is a pioneering biotechnology company using the science of glycomics to discover and develop  drugs that enhance and mimic the innate immune system.

New class of glycopolymer-based therapeutics

Our innovative glycomics platform targets complex cell surface and mucosal interface interactions in diverse clinical ecosystems. The mucosal surface provides the body’s natural barrier to infection and damage from outside contaminants and pathogens.

Our discovery engine has led to breakthrough therapies that change disease progression in pulmonary disorders and optimize oral health.

We continue to leverage these successes to develop gastrointestinal, ophthalmic and sinus care drugs. We have also applied our expertise to develop medical device products to improve wound healing and reduce infection and scar formation.

Creative solutions to difficult chemistry problems and unmet medical needs

Through our highly specialized, robust and predictive technology engine, Synedgen solves difficult chemistry problems previously inaccessible to traditional approaches. We have identified chemical properties required to ultra-purify glycopolymers and designed chemical modifications to make the drugs soluble, active and targeted in the human body.

Our chemistry advantage produces a scientifically validated pipeline of drugs able to:

  • Mimic the body’s innate immune response to reduce inflammation and improve healing.
  • Protect mucosal surfaces from damage and microbial imbalance.
  • Control mucosal inflammation after damage and restore homeostasis.
  • Reduce the ability of bacteria to bind and invade tissues.
  • Restore the native environment to support the normal microbiome.

Ion interactions at the cellular level play key roles driving diseases affecting the mucosal interface and suggest potential therapeutic approaches. For the design of mucosal drug delivery and therapeutics. James D. Sterling and Shenda M. Baker reported this research in Macromolecular Theory and Simulations. Image courtesy of KC Jones.

Intellectual Property

Synedgen has a broad US and international patent estate. The IP portfolio covers the overall platform as well as use and compositions of matter for the specific products under development.